Critical Enzymatic Functions of FTO in Obesity and Cancer

Critical Enzymatic Functions of FTO in Obesity and Cancer

Fat mass and obesity-associated protein (FTO) single-nucleotide polymorphisms (SNPs) have been linked to increased body mass and obesity in humans by genome-wide association studies (GWAS) since 2007. Although some recent studies suggest that the obesity-related SNPs in FTO influence obesity suscept...

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Bibliographic Details
Main Authors: Xiaolan Deng, Rui Su, Savanna Stanford, Jianjun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Endocrinology
Subjects:
fat mass and obesity-associated protein (FTO)
obesity
cancer
mRNA N6-methyladenosine (m6A)
m6A demethylase
AML
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00396/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00396/full

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