Fludarabine as an Adjuvant Improves Newcastle Disease Virus-Mediated Antitumor Immunity in Hepatocellular Carcinoma

In addition to direct oncolysis, oncolytic viruses (OVs) also induce antitumor immunity, also called viro-immunotherapy. Limited viral replication and immune-negative feedback are the major hurdles to effective viro-immunotherapy. In this study, we found that use of an adjuvant of fludarabine, a che...

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Bibliographic Details
Main Authors: Gang Meng, Ziwei Fei, Mingyue Fang, Binghua Li, Anxian Chen, Chun Xu, Mao Xia, Decai Yu, Jiwu Wei
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519300348