Dabrafenib: A narrative drug review

Activating mutations in the BRAF gene lead to an unregulated downstream signaling of the MAPK/extracellular-signal-regulated kinase pathway. This pathway is implicated in a range of solid tumors, and BRAF inhibitors are an attractive option in the treatment of these cancers. At present, three BRAF i...

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Bibliographic Details
Main Authors: Lakhan Kashyap, Saswata Saha, Anne Srikanth
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Cancer Research, Statistics, and Treatment
Subjects:
Online Access:http://www.crstonline.com/article.asp?issn=2590-3233;year=2020;volume=3;issue=3;spage=537;epage=544;aulast=