PFASUM: a substitution matrix from Pfam structural alignments

PFASUM: a substitution matrix from Pfam structural alignments

Abstract Background Detecting homologous protein sequences and computing multiple sequence alignments (MSA) are fundamental tasks in molecular bioinformatics. These tasks usually require a substitution matrix for modeling evolutionary substitution events derived from a set of aligned sequences. Over...

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Bibliographic Details
Main Authors: Frank Keul, Martin Hess, Michael Goesele, Kay Hamacher
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Bioinformatics
Subjects:
Substitution matrix
PFASUM
Homologous sequence search
Sequence alignment
Online Access:http://link.springer.com/article/10.1186/s12859-017-1703-z

Internet

http://link.springer.com/article/10.1186/s12859-017-1703-z

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