Advances in MS Based Strategies for Probing Ligand-Target Interactions: Focus on Soft Ionization Mass Spectrometric Techniques

Advances in MS Based Strategies for Probing Ligand-Target Interactions: Focus on Soft Ionization Mass Spectrometric Techniques

The non-covalent interactions between small drug molecules and disease-related proteins (ligand-target interactions) mediate various pharmacological processes in the treatment of different diseases. The development of the analytical methods to assess those interactions, including binding sites, bind...

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Bibliographic Details
Main Authors: Guilin Chen, Minxia Fan, Ye Liu, Baoqing Sun, Meixian Liu, Jianlin Wu, Na Li, Mingquan Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Chemistry
Subjects:
ligand-target interactions
mass spectrometry
soft ionization
drug discovery
ESI-MS
MALDI-MS
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00703/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2019.00703/full

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