MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis
Melanoma with rapid progression towards metastasis has become the deadliest form of skin cancer. However, the mechanism of melanoma growth and metastasis is still unclear. Here, we found that miRNA-138 was lowly expressed and hypoxia-inducible factor 1α (HIF1α) was highly expressed in patients’ mela...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2019-08-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/8/8/bio042937 |