Lower frequency of TLR9 variant associated with protection from breast cancer among African Americans.

Toll-like receptor 9 (TLR9) is an innate immune system DNA-receptor that regulates tumor invasion and immunity in vitro. Low tumor TLR9 expression has been associated with poor survival in Caucasian patients with triple negative breast cancer (TNBC). African American (AA) patients with TNBC have wor...

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Bibliographic Details
Main Authors: Madison R Chandler, Kimberly S Keene, Johanna M Tuomela, Andres Forero-Torres, Renee Desmond, Katri S Vuopala, Kevin W Harris, Nancy D Merner, Katri S Selander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5590816?pdf=render