Effect of episomally encoded DNA polymerases on chemically induced mutagenesis at the hisG46 target in Ames test
Abstract Background The standard Ames test strains owe their high sensitivity to chemical and physical mutagens to the episomal Y-family DNA polymerase RI encoded by the mucAB operon. The S. typhimurium test strains carry also another related samAB operon on a 60-kDa cryptic plasmid. In contrast to...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-03-01
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| Series: | Genes and Environment |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41021-020-00154-2 |