Regulation of cell-to-cell variability in divergent gene expression

Gene expression noise affects cell fitness and development. Here, Yan et al. show that co-regulated divergent gene pairs (DGPs) suppress uncorrelated gene expression noise due to more synchronized transcription firing, and differentially regulated DGPs enhance gene expression noise due to transcript...

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Bibliographic Details
Main Authors: Chao Yan, Shuyang Wu, Christopher Pocetti, Lu Bai
Format: Article
Language:English
Published: Nature Publishing Group 2016-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11099