High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype

High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype

BACKGROUND & AIMS: Steatohepatitis (SH) and SH-associated hepatocellular carcinoma (HCC) are of considerable clinical significance. SH is morphologically characterized by steatosis, liver cell ballooning, cytoplasmic aggregates termed Mallory-Denk bodies (MDBs), inflammation, and fibrosis at lat...

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Main Authors: Nicole Golob-Schwarzl, Kira Bettermann, Anita Kuldeep Mehta, Sonja M. Kessler, Julia Unterluggauer, Stefanie Krassnig, Kensuke Kojima, Xintong Chen, Yujin Hoshida, Nabeel M. Bardeesy, Heimo Müller, Vendula Svendova, Michael G. Schimek, Clemens Diwoky, Alexandra Lipfert, Vineet Mahajan, Cornelia Stumptner, Andrea Thüringer, Leopold F. Fröhlich, Tatjana Stojakovic, K.P.R. Nilsson, Thomas Kolbe, Thomas Rülicke, Thomas M. Magin, Pavel Strnad, Alexandra K. Kiemer, Richard Moriggl, Johannes Haybaeck
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652331830439X

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http://www.sciencedirect.com/science/article/pii/S193652331830439X

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