Common Medical and Statistical Problems: The Dilemma of the Sample Size Calculation for Sensitivity and Specificity Estimation
Sample size calculation in biomedical practice is typically based on the problematic Wald method for a binomial proportion, with potentially dangerous consequences. This work highlights the need of incorporating the concept of conditional probability in sample size determination to avoid reduced sam...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
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Series: | Mathematics |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-7390/8/8/1258 |