Association of relapse-linked ARID5B single nucleotide polymorphisms with drug resistance in B-cell precursor acute lymphoblastic leukemia cell lines

Association of relapse-linked ARID5B single nucleotide polymorphisms with drug resistance in B-cell precursor acute lymphoblastic leukemia cell lines

Abstract Background The genetic variants of the ARID5B gene have recently been reported to be associated with disease susceptibility and treatment outcome in childhood acute lymphoblastic leukemia (ALL). However, few studies have explored the association of ARID5B with sensitivities to chemotherapeu...

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Bibliographic Details
Main Authors: Minori Tamai, Meixian Huang, Keiko Kagami, Masako Abe, Shinpei Somazu, Tamao Shinohara, Daisuke Harama, Atsushi Watanabe, Koshi Akahane, Kumiko Goi, Kanji Sugita, Hiroaki Goto, Masayoshi Minegishi, Shotaro Iwamoto, Takeshi Inukai
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cancer Cell International
Subjects:
ARID5B
B-cell precursor acute lymphoblastic leukemia
Drug sensitivities
Single nucleotide polymorphism
Online Access:http://link.springer.com/article/10.1186/s12935-020-01524-0

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http://link.springer.com/article/10.1186/s12935-020-01524-0

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