Role of Toll-like receptors in immune activation and tolerance in the liver

Liver has a unique vascular system receiving the majority of the blood supply from the gastrointestinal tract through the portal vein and faces continuous exposure to foreign pathogens and commensal bacterial products. These gut-derived antigens stimulate liver cells and result in a distinctive immu...

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Bibliographic Details
Main Authors: Nobuhiro eNakamoto, Takanori eKanai
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00221/full