Anticancer efficacy of a supramolecular complex of a 2-diethylaminoethyl–dextran–MMA graft copolymer and paclitaxel used as an artificial enzyme

Anticancer efficacy of a supramolecular complex of a 2-diethylaminoethyl–dextran–MMA graft copolymer and paclitaxel used as an artificial enzyme

The anticancer efficacy of a supramolecular complex that was used as an artificial enzyme against multi-drug-resistant cancer cells was confirmed. A complex of diethylaminoethyl–dextran–methacrylic acid methylester copolymer (DDMC)/paclitaxel (PTX), obtained with PTX as the guest and DDMC as the hos...

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Bibliographic Details
Main Authors: Yasuhiko Onishi, Yuki Eshita, Rui-Cheng Ji, Masayasu Onishi, Takashi Kobayashi, Masaaki Mizuno, Jun Yoshida, Naoji Kubota
Format: Article
Language:English
Published: Beilstein-Institut 2014-12-01
Series:Beilstein Journal of Nanotechnology
Subjects:
artificial enzyme
diethylaminoethyl–dextran–MMA
graft copolymer
multi-drug resistance of cancer cells
paclitaxel
supramolecular complex
Online Access:https://doi.org/10.3762/bjnano.5.238

Internet

https://doi.org/10.3762/bjnano.5.238

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