Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure

Cold stress can induce neuronal apoptosis in the hippocampus, but the internal mechanism involving neuronal loss induced by cold stress is not clear. In vivo, male and female C57BL/6 mice were exposed to 4 °C, 3 h per day for 1 week. In vitro, HT22 cells were treated with different concentr...

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Bibliographic Details
Main Authors: Bin Xu, Li-min Lang, Shi-Ze Li, Jing-Ru Guo, Jian-Fa Wang, Di Wang, Li-Ping Zhang, Huan-Min Yang, Shuai Lian
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/6/612