Citrullination of a phage-displayed human peptidome library reveals the fine specificities of rheumatoid arthritis-associated autoantibodies

Background: Post-translational modifications (PTMs) on proteins can be targeted by antibodies associated with autoimmunity. Despite a growing appreciation for their intrinsic role in disease, there is a lack of highly multiplexed serological assays to characterize the fine specificities of PTM-direc...

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Bibliographic Details
Main Authors: Gabriel D. Román-Meléndez, Daniel R. Monaco, Janelle M. Montagne, Rachel S. Quizon, Maximilian F. Konig, Mekbib Astatke, Erika Darrah, H. Benjamin Larman
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421002991