Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese
Abstract Background Exposure to increased manganese (Mn) causes inflammation and neuronal injury in the cortex and basal ganglia, resulting in neurological symptoms resembling Parkinson’s disease. The mechanisms underlying neuronal death from exposure to Mn are not well understood but involve inflam...
Main Authors: | Katriana A. Popichak, Maryam F. Afzali, Kelly S. Kirkley, Ronald B. Tjalkens |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-018-1349-4 |
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