Assorted Processing of Synthetic Trans-Acting siRNAs and Its Activity in Antiviral Resistance.

The use of syn-tasiRNAs has been proposed as an RNA interference technique alternative to those previously described: hairpin based, virus induced gene silencing or artificial miRNAs. In this study we engineered the TAS1c locus to impair Plum pox virus (PPV) infection by replacing the five native si...

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Bibliographic Details
Main Authors: Mingmin Zhao, David San León, Frida Mesel, Juan Antonio García, Carmen Simón-Mateo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4492489?pdf=render