β-caryophyllene improves cerebral ischemia reperfusion injury in rats via Notch1/NF-κB signal axis

β-caryophyllene improves cerebral ischemia reperfusion injury in rats via Notch1/NF-κB signal axis

Objective To explore the protective effect of β-caryophyllene (BCP) on cerebral ischemia-reperfusion (I/R) rats and related mechanism. Methods SD rats were randomized into sham operation group, I/R group, and low-, medium- and high-dose BCP groups (102, 204 and 408 mg·kg-1), Jagged1 (Notch1 agonist,...

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Bibliographic Details
Main Authors: LIU Jingdong, CHEN Sha, WANG Yuchun, LIU Shengwei, RAO Jiangyan, WANG Qian, DENG Ling, WANG Xuan, DONG Zhi
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-02-01
Series:Di-san junyi daxue xuebao
Subjects:
cerebral ischemia-reperfusion injury
β-caryophyllene
inflammation
notch1/nf-κb
Online Access:https://aammt.tmmu.edu.cn/Upload/rhtml/202009067.htm

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https://aammt.tmmu.edu.cn/Upload/rhtml/202009067.htm

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