Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults

Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults

Abstract Background Cognition is closely associated with physical function. Although high brain amyloid-β (Aβ) deposition and neurofilament light chain (NfL) are associated with cognitive and gait speed decline, relationships of combined plasma Aβ and NfL profiles with cognitive and physical functio...

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Bibliographic Details
Main Authors: Lingxiao He, Philipe de Souto Barreto, Geetika Aggarwal, Andrew D. Nguyen, John E. Morley, Yan Li, Randall J. Bateman, Bruno Vellas, For the MAPT/DSA Group
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
Amyloid-β
Neurofilament light chain
Cognitive function
Physical function
Online Access:http://link.springer.com/article/10.1186/s13195-020-00697-0

Internet

http://link.springer.com/article/10.1186/s13195-020-00697-0

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