Regulation of gene expression by PI3K in mouse growth plate chondrocytes.

Endochondral ossification, the process through which long bones are formed, involves chondrocyte proliferation and hypertrophic differentiation in the cartilage growth plate. In a previous publication we showed that pharmacological inhibition of the PI3K signaling pathway results in reduced endochon...

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Bibliographic Details
Main Authors: Veronica Ulici, Claudine G James, Katie D Hoenselaar, Frank Beier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2810323?pdf=render