Discovery of the elusive leptin in birds: identification of several 'missing links' in the evolution of leptin and its receptor.

Leptin is a pleiotropic protein best known for regulation of appetite and fat storage in mammals. While many leptin orthologs have been identified among vertebrates, an authentic leptin in birds has remained elusive and controversial. Here we identify leptin sequence from the Peregrine falcon, Falco...

Full description

Bibliographic Details
Main Authors: Jeremy W Prokop, Cameron Schmidt, Donald Gasper, Robert J Duff, Amy Milsted, Takeshi Ohkubo, Hope C Ball, Matthew D Shawkey, Herman L Mays, Larry A Cogburn, Richard L Londraville
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3963946?pdf=render