Organotypic Cultures as a Model of Parkinson´s Disease. A Twist to an Old Model

Organotypic cultures from the ventral mesencephalon (VM) are widely used to model Parkinson's disease (PD). In this method, neurotoxic compounds have traditionally been applied to the media to induce a uniform dopaminergic (DAergic) cell death in the tissue slices, regardless of the variation e...

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Bibliographic Details
Main Authors: Katja Stahl, øivind Skare, Reidun Torp
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2009.68