The Armadillo (Dasypus novemcinctus): A Witness but Not a Functional Example for the Emergence of the Butyrophilin 3/Vγ9Vδ2 System in Placental Mammals

The Armadillo (Dasypus novemcinctus): A Witness but Not a Functional Example for the Emergence of the Butyrophilin 3/Vγ9Vδ2 System in Placental Mammals

1–5% of human blood T cells are Vγ9Vδ2 T cells whose T cell receptor (TCR) contain a TRGV9/TRGJP rearrangement and a TRDV2 comprising Vδ2-chain. They respond to phosphoantigens (PAgs) like isopentenyl pyrophosphate or (E)-4-hydroxy-3-methyl-but-2-enyl-pyrophosphate (HMBPP) in a butyrophilin 3 (BTN3)...

Full description

Bibliographic Details
Main Authors: Alina Suzann Fichtner, Mohindar Murugesh Karunakaran, Lisa Starick, Richard W. Truman, Thomas Herrmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
Vγ9Vδ2
TRGV9
TRDV2
butyrophilin 3
coevolution
nine-banded armadillo
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00265/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00265/full

Similar Items