Jmjd3 mediates blood–spinal cord barrier disruption after spinal cord injury by regulating MMP-3 and MMP-9 expressions

The disruption of the blood–spinal cord barrier (BSCB) by matrix metalloprotease (MMP) activation is a detrimental event that leads to blood cell infiltration, inflammation, and apoptosis, thereby contributing to permanent neurological disability after spinal cord injury (SCI). However, the molecula...

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Bibliographic Details
Main Authors: Jee Y. Lee, Won H. Na, Hae Y. Choi, Kwang H. Lee, Bong G. Ju, Tae Y. Yune
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611630170X