The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity
Abstract The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (Ro), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU). We suggest that comparison between the two parameters may assist in bette...
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| Format: | Article |
| Language: | English |
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BMC
2021-04-01
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| Series: | Virology Journal |
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| Online Access: | https://doi.org/10.1186/s12985-021-01566-4 |
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doaj-8277853edf454698847be8e7185d2cac2021-05-02T11:26:38ZengBMCVirology Journal1743-422X2021-04-011811410.1186/s12985-021-01566-4The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivityWinston McCormick0Leonard A. Mermel1Warren Alpert Medical School of Brown UniversityDepartment of Medicine, Warren Alpert Medical School of Brown UniversityAbstract The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (Ro), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU). We suggest that comparison between the two parameters may assist in better understanding viral transmission dynamics.https://doi.org/10.1186/s12985-021-01566-4Basic reproductive numberParticle-to-plaqueParticle-to-pfuCOVID-19Viral transmission |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Winston McCormick Leonard A. Mermel |
| spellingShingle |
Winston McCormick Leonard A. Mermel The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity Virology Journal Basic reproductive number Particle-to-plaque Particle-to-pfu COVID-19 Viral transmission |
| author_facet |
Winston McCormick Leonard A. Mermel |
| author_sort |
Winston McCormick |
| title |
The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity |
| title_short |
The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity |
| title_full |
The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity |
| title_fullStr |
The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity |
| title_full_unstemmed |
The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity |
| title_sort |
basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity |
| publisher |
BMC |
| series |
Virology Journal |
| issn |
1743-422X |
| publishDate |
2021-04-01 |
| description |
Abstract The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (Ro), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU). We suggest that comparison between the two parameters may assist in better understanding viral transmission dynamics. |
| topic |
Basic reproductive number Particle-to-plaque Particle-to-pfu COVID-19 Viral transmission |
| url |
https://doi.org/10.1186/s12985-021-01566-4 |
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