The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity

Abstract The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (Ro), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU). We suggest that comparison between the two parameters may assist in bette...

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Bibliographic Details
Main Authors: Winston McCormick, Leonard A. Mermel
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-021-01566-4