Tum/RacGAP functions as a switch activating the Pav/kinesin-6 motor
Centralspindlin consists of dimeric kinesin-6 and dimeric RacGAP, and is involved in the organization of anaphase midzone microtubules. Here, the authors show that the RacGAP is needed for motor activity at the plus-end of microtubules, but not for the bundling activity associated with kinesin-6.
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016-04-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms11182 |