Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding
The decarboxylate enzyme Fdc1 requires a prenylated flavin mononucleotide co-factor for activity. Here, the authors use a variety of mass spectrometric techniques to observe the structural changes in this protein in response to co-factor binding.
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms12163 |