ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion

<p>Abstract</p> <p>Background</p> <p>Previous studies suggested that the RhoA/ROCK pathway may contribute to vascular complications in diabetes. The present study was designed to investigate whether ROCK inhibitor fasudil could prevent high glucose-induced monocyte-endo...

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Bibliographic Details
Main Authors: Li Hailing, Peng Wenhui, Jian Weixia, Li Yuanmin, Li Qi, Li Weiming, Xu Yawei
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:http://www.cardiab.com/content/11/1/65