HIF1α-Dependent Metabolic Signals Control the Differentiation of Follicular Helper T Cells

HIF1α-Dependent Metabolic Signals Control the Differentiation of Follicular Helper T Cells

Follicular helper T (T<sub>FH</sub>) cells are critical for germinal center (GC) formation and are responsible for effective B cell-mediated immunity; metabolic signaling is an important regulatory mechanism for the differentiation of T<sub>FH</sub> cells. However, the precis...

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Bibliographic Details
Main Authors: Lin Dong, Ying He, Shuping Zhou, Yejin Cao, Yan Li, Yujing Bi, Guangwei Liu
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
follicular helper t cell
t cell differentiation
hif1α
glycolysis
oxidative phosphorylation
virus infection
infectious inflammation
gc responses
b cell immunity
Online Access:https://www.mdpi.com/2073-4409/8/11/1450

Internet

https://www.mdpi.com/2073-4409/8/11/1450

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