Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids
Abstract Mortalin (Mot) is a mitochondrial chaperone of the heat shock protein 70 family and it’s pro-proliferative and anti-apoptosis functions could be associated with keloid pathogenesis, and blocking of mortalin and its interaction with p53 might be a potential novel target for the treatment of...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-13485-y |