Inducing Oncoprotein Degradation to Improve Targeted Cancer Therapy

Over the past decade, inhibition of the kinase activities of oncogenic proteins using small molecules and antibodies has been a mainstay of our anticancer drug development effort, resulting in several Food and Drug Administration–approved cancer therapies. The clinical effectiveness of kinase-target...

Full description

Bibliographic Details
Main Authors: Dipankar Ray, Kyle C. Cuneo, Alnawaz Rehemtulla, Theodore S. Lawrence, Mukesh K. Nyati
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558615001049