Identification and Characterization of Three Novel Small Interference RNAs That Effectively Down-Regulate the Isolated Nucleocapsid Gene Expression of SARS Coronavirus

Nucleocapsid (N) protein of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is a major pathological determinant in the host that may cause host cell apoptosis, upregulate the proinflammatory cytokine production, and block innate immune responses. Therefore, N gene has long been t...

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Bibliographic Details
Main Authors: Ying-Li Cao, Li Liu, Shu-Hui Wang, Yun Zhang, Fan Yang, Rong Guo, Ying Wang
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/2/1544/