Postsynaptic densities fragment into subcomplexes upon sonication

Abstract Postsynaptic density (PSD) fractions were isolated from rat forebrain and sonicated. Pellets from sonicated samples examined by electron microscopy revealed particles with an electron density similar to PSDs that appeared to be fragments of PSDs. Immuno-gold labeling confirmed that some of...

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Bibliographic Details
Main Authors: Ayse Dosemeci, Jung-Hwa Tao-Cheng, Valerie Bakly, Thomas S. Reese
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Molecular Brain
Subjects:
PSD
EM
Online Access:http://link.springer.com/article/10.1186/s13041-019-0491-y