Valine-mediated borane reduction of ketones

Acetophenone, 3,3-dimethyl-2-butanone, 3-methyl-2-butanone, and 2-penta-none were reduced with (S)-valine-mediated borane in very good yields (86-91%) giving predominantly alcohols of the (R)-configuration (80, 64, 55, and 36 % ее, respectively).

Bibliographic Details
Main Authors: Teodorović A.V., Joksović M.D., Konstantinović S.K., Milovanović J.N., Mojsilović В.M.
Format: Article
Language:English
Published: Serbian Chemical Society 2000-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2000/0352-51390008549T.pdf