Spatiotemporally Controlled Myosin Relocalization and Internal Pressure Generate Sibling Cell Size Asymmetry

Summary: Metazoan cells can generate unequal-sized sibling cells during cell division. This form of asymmetric cell division depends on spindle geometry and Myosin distribution, but the underlying mechanics are unclear. Here, we use atomic force microscopy and live cell imaging to elucidate the biop...

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Bibliographic Details
Main Authors: Tri Thanh Pham, Arnaud Monnard, Jonne Helenius, Erik Lund, Nicole Lee, Daniel J. Müller, Clemens Cabernard
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219300367