A high-throughput protocol for mutation scanning of the <it>BRCA1 </it>and <it>BRCA2 </it>genes

<p>Abstract</p> <p>Background</p> <p>Detection of mutations by DNA sequencing can be facilitated by scanning methods to identify amplicons which may have mutations. Current scanning methods used for the detection of germline sequence variants are laborious as they requi...

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Bibliographic Details
Main Authors: Wong Stephen Q, Scott Rodney J, Beshay Victoria, Mitchell Gillian, Fox Stephen B, Hondow Heather L, Dobrovic Alexander
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/265