PRMT3 interacts with ALDH1A1 and regulates gene-expression by inhibiting retinoic acid signaling

PRMT3 interacts with ALDH1A1 and regulates gene-expression by inhibiting retinoic acid signaling

Here, the authors demonstrate that protein arginine methyltransferase 3 (PRMT3) interacts with and inhibits the retinal dehydrogenase ALDH1A1, negatively regulating the expression of retinoic acid responsive genes. This study shows that PRMT3 affects diverse biological processes not only by globally...

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Bibliographic Details
Main Authors: Mamta Verma, Mohd. Imran K. Khan, Rajashekar Varma Kadumuri, Baskar Chakrapani, Sharad Awasthi, Arun Mahesh, Gayathri Govindaraju, Pavithra L Chavali, Arumugam Rajavelu, Sreenivas Chavali, Arunkumar Dhayalan
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01644-3

Internet

https://doi.org/10.1038/s42003-020-01644-3

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