General Method for the Synthesis of (−)-Conduritol C and Analogs from Chiral Cyclohexadienediol Scaffolds

General Method for the Synthesis of (−)-Conduritol C and Analogs from Chiral Cyclohexadienediol Scaffolds

An efficient and facile general method for the synthesis of conduritol C analogs, taking advantage of an enantioselective biocatalysis process of monosubstituted benzenes, is described. The absolute stereochemical patterns of the target molecules (−)-conduritol C, (−)-bromo-condu...

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Bibliographic Details
Main Authors: Gaurao D. Tibhe, Mario A. Macías, Valeria Schapiro, Leopoldo Suescun, Enrique Pandolfi
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
conduritol C
enantioselective biocatalysis
arene biotransformation
crystal structures
α-glycosidase inhibitors
Online Access:http://www.mdpi.com/1420-3049/23/7/1653

Internet

http://www.mdpi.com/1420-3049/23/7/1653

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