Issues associated with assessing nuclear localization of N-terminally unphosphorylated β-catenin with monoclonal antibody 8E7

<p>Abstract</p> <p>Background</p> <p>β-catenin is a dual function adhesion/transcriptional co-activator protein, and both functions are critical for normal tissue homeostasis. Since the transcriptional functions of β-catenin are more often implicated in various disease...

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Bibliographic Details
Main Authors: Russell Susan, Hartsell Alyssa M, Flozak Annette S, Maher Meghan T, Beri Rohinee, Peled Ofra N, Gottardi Cara J
Format: Article
Language:English
Published: BMC 2009-02-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/4/1/5