The Role of Nrf2 in Liver Disease: Novel Molecular Mechanisms and Therapeutic Approaches

Oxidative stress and inflammation are the most important pathogenic events in the development and progression of liver diseases. Nuclear erythroid 2-related factor 2 (Nrf2) is the master regulator of the cellular protection via induction of anti-inflammatory, antioxidant, and cyto-protective genes e...

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Bibliographic Details
Main Authors: Dongwei Xu, Min Xu, Seogsong Jeong, Yihan Qian, Hailong Wu, Qiang Xia, Xiaoni Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01428/full