Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines

Over the last few years, we have been evaluating a novel paradigm for immunization using viruses or virus-based vectors. Safety is provided not by attenuation or inactivation of vaccine viruses, but by the introduction into the viral genomes of genetic mechanisms that allow for stringent, deliberate...

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Bibliographic Details
Main Authors: Richard Voellmy, David C Bloom, Nuria Vilaboa
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/2/230