Concentration dependent ion selectivity in VDAC: a molecular dynamics simulation study.

The voltage-dependent anion channel (VDAC) forms the major pore in the outer mitochondrial membrane. Its high conducting open state features a moderate anion selectivity. There is some evidence indicating that the electrophysiological properties of VDAC vary with the salt concentration. Using a theo...

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Bibliographic Details
Main Authors: Eva-Maria Krammer, Fabrice Homblé, Martine Prévost
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3229507?pdf=render