Polymorphism in the alpha cardiac muscle actin 1 gene is associated to susceptibility to chronic inflammatory cardiomyopathy.

AIMS: Chagas disease, caused by the protozoan Trypanosoma cruzi is endemic in Latin America, and may lead to a life-threatening inflammatory dilated, chronic Chagas cardiomyopathy (CCC). One third of T. cruzi-infected individuals progress to CCC while the others remain asymptomatic (ASY). A possible...

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Main Authors: Amanda Farage Frade, Priscila Camilo Teixeira, Barbara Maria Ianni, Cristina Wide Pissetti, Bruno Saba, Lin Hui Tzu Wang, Andréia Kuramoto, Luciana Gabriel Nogueira, Paula Buck, Fabrício Dias, Helene Giniaux, Agnes Llored, Sthefanny Alves, Andre Schmidt, Eduardo Donadi, José Antonio Marin-Neto, Mario Hirata, Marcelo Sampaio, Abílio Fragata, Edimar Alcides Bocchi, Antonio Noedir Stolf, Alfredo Inacio Fiorelli, Ronaldo Honorato Barros Santos, Virmondes Rodrigues, Alexandre Costa Pereira, Jorge Kalil, Edecio Cunha-Neto, Christophe Chevillard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3868584?pdf=render