Intratumoral immunosuppression profiles in 11q‐deleted neuroblastomas provide new potential therapeutic targets

Intratumoral immunosuppression profiles in 11q‐deleted neuroblastomas provide new potential therapeutic targets

High‐risk neuroblastoma (NB) patients with 11q deletion frequently undergo late but consecutive relapse cycles with fatal outcome. To date, no actionable targets to improve current multimodal treatment have been identified. We analyzed immune microenvironment and genetic profiles of high‐risk NB cor...

Full description

Bibliographic Details
Main Authors: Esther Coronado, Yania Yañez, Enrique Vidal, Luis Rubio, Francisco Vera‐Sempere, Antonio José Cañada‐Martínez, Joaquín Panadero, Adela Cañete, Ruth Ladenstein, Victoria Castel, Jaime Font de Mora
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Molecular Oncology
Subjects:
11q deletion
anti‐GD2 immunotherapy
combination immunotherapy
immune cell infiltration
miRNAs
neuroblastoma
Online Access:https://doi.org/10.1002/1878-0261.12868

Internet

https://doi.org/10.1002/1878-0261.12868

Similar Items