TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation.
Although much effort has been directed at dissecting the mechanisms of central tolerance, the role of thymic stromal cells remains elusive. In order to further characterize this event, we developed a mouse model restricting LacZ to thymic stromal cotransporter (TSCOT)-expressing thymic stromal cells...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-08-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC2494558?pdf=render |