Gene regulatory networks from multifactorial perturbations using Graphical Lasso: application to the DREAM4 challenge.

A major challenge in the field of systems biology consists of predicting gene regulatory networks based on different training data. Within the DREAM4 initiative, we took part in the multifactorial sub-challenge that aimed to predict gene regulatory networks of size 100 from training data consisting...

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Bibliographic Details
Main Authors: Patricia Menéndez, Yiannis A I Kourmpetis, Cajo J F ter Braak, Fred A van Eeuwijk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21188141/?tool=EBI