Regulation of Tau Protein on the Antidepressant Effects of Ketamine in the Chronic Unpredictable Mild Stress Model

Regulation of Tau Protein on the Antidepressant Effects of Ketamine in the Chronic Unpredictable Mild Stress Model

Tau protein is known to play an important role in maintaining microtubule assembly and stabilization, and maintaining the normal morphology of neurons, but several studies have found that chronic stress leads to Tau hyperphosphorylation. A large number of clinical trials have found that ketamine, wh...

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Bibliographic Details
Main Authors: Gehua Wen, Hui Yao, Yanning Li, Runtao Ding, Xinghua Ren, Yaqing Tan, Weishu Ren, Hao Yu, Xiaoni Zhan, Xiaolong Wang, Enyu Xu, Jun Yao, Guohua Zhang, Yan Lu, Xu Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Psychiatry
Subjects:
depression
hippocampus
Tau protein phosphorylation
synapse
ketamine
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00287/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2019.00287/full

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