Suppression of lncRNA NLRP3 inhibits NLRP3-triggered inflammatory responses in early acute lung injury

Abstract Acute lung injury (ALI) is a common lung pathology that is accompanied by alveolar macrophage (AM) activation and inflammatory response. This study investigated the role of the long non-coding RNA NONRATT004344 (hereafter named lncRNA NLRP3) in regulating the Nod-like receptor protein 3 (NL...

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Bibliographic Details
Main Authors: Deqiang Luo, Wei Dai, Xiaojin Feng, Chengzhi Ding, Qiang Shao, Rui Xiao, Ning Zhao, Wei Peng, Ying Yang, Yamei Cui, Fen Liu, Kejian Qian
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04180-y